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AlphaGenome 2 predicts DNA effects at cell-type resolution

Google DeepMind released AlphaGenome 2, a DNA sequence model trained on more than 100 million cell profiles across 68 tissues. It predicts how genetic variants affect specific cell types and states and is accessible through the AlphaGenome API for non-commercial research.

Why it matters: Moving from tissue averages to cell-specific predictions can help researchers prioritize variants that broad models miss. The release is a research instrument, not clinical evidence or a diagnostic system.

Read storyOriginal source · deepmind.google